COVID Moonshot

Project developing antiviral drug

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June 2023 Projected start of Phase-1 clinical trials for the COVID Moonshot antiviral drug candidate targeting the Mpro protein of coronaviruses.
March 2022 COVID Moonshot aims to select three pre-clinical candidates for potential antiviral treatments against COVID-19.
January 2021 Unique compound design submissions reached 14,000, prompting the project to transition from a spontaneous virtual collaboration to a more organized network of specialized partners.
May 2020 Over 4,600 design submissions for potential inhibitors received, significantly exceeding the project's initial expectations.
March 7 2020 COVID Moonshot project launched with open data release and Twitter announcement, challenging chemists worldwide to design potential antiviral drug candidates.
January 26 2020 Zihe Rao and Haitao Yang submitted a structure of SARS-CoV-2 main protease (Mpro) bound to an inhibitor to the Protein Data Bank, providing crucial early X-ray crystallography insights into the virus's key protein.
January 11 2020 Edward C. Holmes of the University of Sydney publicly releases the virus genome with Zhang's permission.
January 5 2020 Zhang and his team successfully sequence the virus from the sample and deposit its genome on GenBank, an international research database.
January 3 2020 Chinese virologist Yong-Zhen Zhang of Fudan University receives a test sample from Wuhan, China containing patients with a pneumonia-like illness.

This contents of the box above is based on material from the Wikipedia article COVID Moonshot, which is released under the Creative Commons Attribution-ShareAlike 4.0 International License.

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