Monoclonal antibodies

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We include updates on Dupilumab, Adalimumab, Denosumab, Infliximab, Risankizumab, Evolocumab, Secukinumab, Omalizumab, Vedolizumab, Guselkumab, Galcanezumab, Tocilizumab, Lokivetmab, Lecanemab, Ustekinumab, TNF inhibitor ... and more.

March 2024
Monoclonal antibody
US FDA granted emergency use authorization to pemivibart, a monoclonal antibody drug, for pre-exposure prophylaxis in moderately to severely immunocompromised individuals against COVID-19.
July 2023
Monoclonal antibody therapy
The FDA granted full approval to Lecanemab (commercial name Leqembi) for the treatment of Alzheimer's Disease, marking a significant milestone in monoclonal antibody therapy for the condition.
2022
Monoclonal antibody
Cochrane reviews found insufficient evidence for using neutralizing monoclonal antibodies to treat COVID-19 infections, with studies limited to existing COVID-19 variants.
2021
Monoclonal antibody
Cochrane reviews found insufficient evidence for using neutralizing monoclonal antibodies to treat COVID-19 infections in unvaccinated individuals.
September 2021
Monoclonal antibody
Biden administration purchased billions of dollars worth of Regeneron monoclonal antibodies at $2,100 per dose to address COVID-19 treatment shortages.
2020
Monoclonal antibody
US Food and Drug Administration granted emergency use authorizations for monoclonal antibody therapies bamlanivimab/etesevimab and casirivimab/imdevimab to reduce COVID-19 hospitalizations, emergency room visits, and deaths.
June 2019
Monoclonal antibody therapy
Polatuzumab vedotin (Polivy) approved, targeting CD79B.
September 2018
Monoclonal antibody therapy
Cemiplimab (Libtayo) approved, targeting PD-1.
September 2018
Monoclonal antibody therapy
Moxetumomab pasudotox (Lumoxiti) approved, targeting CD22.
August 2018
Monoclonal antibody therapy
Mogamulizumab (Poteligeo) approved, targeting CCR4.
December 2012
Monoclonal antibody therapy
DIAN-TU study launched, focusing on young patients with genetic mutations that are risk factors for Alzheimer's Disease. The study investigates Solanezumab and Gautenerumab as potential preventive treatments.

This contents of the box above is based on material from the Wikipedia articles Monoclonal antibody therapy & Monoclonal antibody, which are released under the Creative Commons Attribution-ShareAlike 4.0 International License.