Pharmacokinetics
Branch of pharmacology
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We include updates on Blood–brain barrier, Route of administration, Therapeutic index, Cytochrome P450, Biological half-life, Bioavailability, Grapefruit–drug interactions, Prodrug, Microdosing, First pass effect, Drug metabolism, Dosage form, Modified-release dosage, Plasma protein binding, Drug interaction, Polypharmacy ... and more.
| 2010 | P450 Compound 1, a highly reactive intermediate in the cytochrome P450 enzyme mechanism, was first isolated. This iron(IV) oxo species has an additional oxidizing equivalent delocalized over the porphyrin and thiolate ligands. |
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